What the Comments Reveal (Beyond Views & Likes)
6.9M views and 158K likes — “The Anatomy of THC cannabinoids” by the Institute of Human Anatomy (Jeremy Jones and Jonathan Bennion) as of 2025-10-15. Out of 13,580 total comments, we analyzed a representative sample of 1,000 to uncover how engaged viewers truly think and feel.
Sentiment Snapshot
The overall tone was positive (48.3%), reflecting curiosity and appreciation for the clarity of scientific explanations, with few negative sentiments.
Emotional Pulse: Curiosity Leads the Way
Viewers were largely intrigued and appreciative, treating the video as both educational and entertaining. Curiosity and amusement dominated, reflecting a thirst for deeper understanding rather than controversy.
Comment Breakdown: Questions and Personal Stories Dominate
The discussion blends curiosity-driven questions, firsthand experiences, and appreciative compliments — a mix signaling both learning and lived connection to the topic.
Jeremy Jones & Jonathan Bennion’s Engagement in the Comments
Interaction was minimal — only about 1 in 250 comments received a direct creator response or heart, suggesting untapped opportunities to nurture community dialogue.
Burning Questions
Viewers pressed hardest for clarity on health risks and safety — especially regarding pregnancy, breastfeeding, and long-term exposure. They asked about psychosis, anxiety, heart rhythm effects, and whether THC interacts with medications like SSRIs, beta blockers, or painkillers through liver metabolism. Many compared vaping, smoking, and edibles to understand which poses fewer risks, and sought timelines for THC clearance and withdrawal recovery.
Curiosity extended to the endocannabinoid system itself — why it exists, how CB1 and CB2 receptors work, and how cannabinoids such as CBD, CBG, and delta-8/9/10 differ. They wanted insight into effects on mood, focus, and conditions like ADHD, PTSD, and dementia, alongside mechanisms driving appetite, creativity, and tolerance shifts.
Feedback and Critiques
Viewers praised the channel’s clarity and educational tone but requested more depth on neurochemistry, hormone interactions, and long-term outcomes. Many highlighted the need for comparisons across routes of use (smoking vs vaping vs edibles) and across substances like caffeine or psychedelics. Others asked for greater balance between benefits and harms — particularly around lung toxicity, addiction, and cognitive effects.
Constructive requests emphasized organ-specific focus (lungs, thyroid, uterus), clearer timelines for THC detection and fat re-release, and detailed imaging comparisons between users and non-users. Overall, feedback points to a highly engaged audience craving scientific precision without losing accessibility.
High Praise
Viewers overwhelmingly lauded the evidence-based and respectful presentation style. The use of real anatomy made complex topics approachable, earning trust across med students, educators, and casual learners alike. Many said it was the first time cannabis effects “finally made sense.”
The team was commended for professionalism, empathy toward donors, and turning anatomy into captivating education. Comments frequently declared the channel among YouTube’s best, with fans eager for more videos exploring THC’s interaction with dopamine, endorphins, and strain differences.
Opportunities for Future Content
- Cannabis during pregnancy and breastfeeding — clarifying prenatal exposure, developmental risks, and clinical guidance.
- Consumption methods — combustion vs vaporization vs edibles and their biological differences.
- Cannabis–medication interactions via CYP450 and liver metabolism.
- Mental health under THC — anxiety, depression, ADHD, psychosis, and age vulnerability.
- Beyond THC — mapping cannabinoids and terpenes for personalized effects.
- THC withdrawal and recovery — timelines, reversibility, and harm reduction strategies.
Looking for the Best YouTube Videos Explaining Cannabis & Its Effects?
We analyzed 9 of YouTube’s most-viewed videos about cannabis, THC, and CBD — collectively watched by over 35 million viewers. See which ones deliver the most trusted, science-backed insights on cannabis’s effects on the brain, sleep, and mental health.
👉 Read the Full Cannabis ReportWrapping Up
This audience values credible science, clear visuals, and balanced discussion. Greater creator interaction and deeper follow-ups on neurochemistry, safety, and personalization could further strengthen trust. Shono AI helps spotlight these signals, ensuring every future video builds on what viewers truly care about.
About This Analysis
Methodology & Limits
We analyzed 1,000 comments from 13,580 total, excluding spam and duplicates. Shono AI classified each comment by sentiment, emotion, and type, aggregating the results for meaningful insight.
Engagement rates reflect the sampled set only. Snapshot as of 2025-10-15; values may evolve as new comments appear.