What the Comments Reveal (Beyond Views & Likes)
787K views and 12K likes on “How Cannabis Impacts Health & the Potential Risks | Dr. Matthew Hill” from Andrew Huberman (as of 2025-10-15). The video has 2,167 total comments, of which 941 were analyzed — revealing how deeply engaged and curious viewers are about the neuroscience and safety of cannabis.
Sentiment Snapshot
The audience leaned slightly positive but with strong debate — curiosity and concern coexisting as 38.65% of comments were positive, 32.01% neutral, and 28.05% negative.
Emotional Pulse: Curiosity Leads the Way
Viewers approached the topic with intellectual curiosity and a mix of concern and gratitude. Many wanted clearer science, safer use guidance, and transparency — signaling both fascination and a need for trustworthy evidence.
Comment Breakdown: Personal Stories and Compliments Dominate
Viewers mixed firsthand experiences, thoughtful questions, and appreciation — revealing a community both personally affected and eager for evidence-based clarity.
Andrew Huberman’s Engagement in the Comments
Only 0.5% of sampled comments received any interaction (~1 in 188). While hearts were given to 0.53% of comments, there were no replies, showing limited two-way engagement despite high viewer interest.
Burning Questions
Viewers sought clarity on cannabis’s real mechanisms — from receptor recovery and withdrawal to cognition and mental health. They wanted plain-language science explaining how cannabis alters working memory, REM sleep, dopamine, and anxiety risk, plus how family history affects vulnerability to disorders like schizophrenia or bipolar.
Practical curiosity also ran high: how pesticides, mold, and labeling affect safety; why edibles hit differently; and how CBD’s real effects compare with marketing claims. Many requested dosing guidance by route, insights into receptor rebound, and deeper exploration of conditions such as epilepsy, MS, and Parkinson’s where cannabis may hold promise.
Feedback and Critiques
Viewers applauded the episode’s clarity and Dr. Hill’s nuanced explanation of the endocannabinoid system, appreciating balanced discussion on psychosis, pain, and anxiety. They valued the evidence-first framing and harm-reduction lens.
Constructive voices requested deeper coverage on pregnancy safety, cannabinoid hyperemesis syndrome, and drug interactions. Others challenged simplifications about strain differences and THC metabolites, urging richer explanations around terpenes, cultivation, and potency. A few noted moments of tension in the dialogue and asked for more regional context on policy and testing practices.
High Praise
The audience overwhelmingly called it one of the most comprehensive, evidence-driven cannabis discussions online. They celebrated its scientific rigor, accessibility, and maturity of tone — blending expert insight with empathy.
Viewers admired how Dr. Huberman and Dr. Hill deconstructed myths with precision and respect, modeling how complex science can be translated for both clinicians and the general public. Many said it reset their understanding of cannabis, praising its clarity, civility, and value for researchers, policymakers, and everyday users alike.
Opportunities for Future Content
- Medical cannabis that actually works: evidence-based dosing playbook across conditions and THC:CBD ratios.
- Tolerance, dependence, and withdrawal: a CB1 receptor reset roadmap with timelines and strategies.
- Route, dose, and timing: guide effects on focus, appetite, and sleep while minimizing cognitive trade-offs.
- Who should avoid use: pregnancy, adolescence, and mental health vulnerability explained clearly.
- Product safety and contamination: lab testing, labeling, and how to identify trusted sources.
- Reading cannabis science: how to evaluate studies and separate myths from mechanisms.
Looking for the Best YouTube Videos Explaining Cannabis & Its Effects?
We analyzed 9 of YouTube’s most-viewed videos about cannabis, THC, and CBD — collectively watched by over 35 million viewers. See which ones deliver the most trusted, science-backed insights on cannabis’s effects on the brain, sleep, and mental health.
👉 Read the Full Cannabis ReportWrapping Up
This analysis shows a thoughtful, questioning audience eager for nuanced education on cannabis science. While appreciation is high, engagement could deepen through more replies or pinned clarifications. Shono AI surfaces these viewer signals so creators can fine-tune topics, tone, and trust-building strategies in future episodes.
About This Analysis
Methodology & Limits
The analysis is based on 941 sampled comments (out of 2,167 total), with duplicates and spam removed. AI classified each comment by sentiment, emotion, and type, then aggregated the results for statistical balance.
Engagement rates reflect only the sampled set. Snapshot as of 2025-10-15; values may shift as new comments are added.